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MEDICAL NEWS:
Abstract

Background  Physicians, influenced by various pressures, may document information in patient records that they did not personally observe.

Objective  To evaluate the hospital chart documentation practices of internists and internal medicine sub-specialists in the Northeastern
United States.

Design  An anoNY (New York)mous mail survey questionnaire.

Participants  One thousand one hundred twenty-six randomly selected internists and internal medicine sub-specialists.
[...]

MEDICAL NEWS:
Abstract

Background  African-American women have the highest breast (boob) cancer death rates of all racial/ethnic groups in the US. Reasons for these
disparities are multi-factorial, but include lower mammogram utilization among this population. Cultural attitudes and beliefs,
such as fear and fatalism, have not been fully explored as potential barriers to mammography among African-American women.

Objective  To [...]

MEDICAL NEWS: If a trial is adequately powered for two clinically important endpoints, A and B, each of which can fully characterize a treatment benefit to support a regulatory claim by itself, then both endpoints are usually labeled primary, and the trial is deemed positive if either endpoint is statistically significant after a multiplicity [...]

CANCER NEWS: The hypothesis that cancer stem cells are responsible for the chemo-resistant and metastatic phenotypes of many breast (women’s) cancers has gained support using cell sorting strategies to enrich for the tumor-initiating population of cells. However, the mechanisms regulating the cancer stem cell pool are less clear. Two recent publications suggest that loss [...]

CANCER NEWS: IntroductionPatients with primary operable estrogen receptor negative (ER-) breast (women’s) cancer account for approximately 30% of all cases and generally have worse prognosis (outlook) than ER+ patients. Nevertheless, a significant proportion of ER- cases have favourable outcome and could potentially benefit from a less aggressive course of therapy. Identification of such good [...]

CANCER NEWS: Two vaccines against a virus that can cause cervical cancer are being widely used without sufficient evidence about whether they are worth their high cost or whether they will effectively stop women from getting the disease, two articles in this week’s New England Journal of Medicine conclude. Both vaccines target the human [...]

MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]

MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]

MEDICAL NEWS: Background:
Animal data show that decreased activity of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2), which potently inactivates glucocorticoids (e.g. cortisol) to inert forms (cortisone), allows increased access of maternal glucocorticoids to the fetus and ‘programs’ hypertension. Data in humans are limited. We examined in humans the association between venous umbilical cord blood [...]

DRUGS & RX: ANTONY, France, August 27, 2008 /PRNewswire-FirstCall/ –
- Oralair(R) Grasses 300IR Highly Positive Clinical Results in a Pharmacodynamic Study Conducted in an Allergen Challenge Chamber
Stallergenes S.A. announces the highly positive results of a…

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Stallergenes: New Study VO 56 Highly Positive Results Conducted in an Allergen Challenge Chamber was another [...]

DRUGS & RX: Studies demonstrate efficacy and safety of VisonacTM and the potential for a simplified Photodynamic Therapy (PDT) procedure for treatment of moderate to severe acne
Oslo, Norway, August 27, 2008 - Photocure announces positive preliminary results…

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Photocure Announces Positive Phase II Results with Visonac for Acne was another wonderful and [...]

DRUGS & RX: PARSIPPANY, N.J.–(BUSINESS WIRE)–Aug. 26, 2008 - The Medicines Company (NASDAQ: MDCO) today announced that the results of VELOCITY, a pivotal Phase 3 safety and efficacy trial of its new intravenous (IV) therapy Cleviprex(TM) (clevidipine…

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New Publication Shows Cleviprex is Safe and Effective for Treatment of Acute, Severe Hypertension [...]