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CANCER NEWS: Actress Jamie Lee Curtis surprised many of her fans this year by being featured in commercials for the Dannon Company’s Activia yogurts discussing the importance of digestive health. In the glamorous world of Hollywood, not many actresses would want to discuss bowel irregularity on national television. But Curtis has become part of [...]

DRUGS & RX: INDIANAPOLIS, August 26, 2008 /PRNewswire/ — Semafore Pharmaceuticals Inc. presented data at the Seventh International Congress on Targeted Therapies in Cancer in Washington, D.C., announcing the discovery of novel multi-targeted kinase inhibitors…

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Semafore Broadens Pipeline With Multi-Targeted Kinase Inhibitors was another wonderful and informative drug and pharmaceutical article [...]

DRUGS & RX: INDIANAPOLIS, August 26, 2008 /PRNewswire/ — Semafore Pharmaceuticals Inc. announced data presented at the Seventh International Congress on Targeted Therapies in Cancer in Washington, D.C., showing additional antiangiogenic activity of…

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SF1126, Semafore’s PI3 Kinase Inhibitor, Found to Block Angiogenic Signaling From Both VEGF and Bv8 in Multiple Cell [...]

DRUGS & RX: CORAL GABLES, Fla., Aug 21, 2008 /PRNewswire-FirstCall/ — Catalyst Pharmaceutical Partners, Inc. today reported that animal data from a new study sponsored by scientists at the U.S. Department of Energy’s Brookhaven National Laboratory appears…

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Catalyst Pharmaceutical Partners Announces Publication of Animal Data Demonstrating Vigabatrin Effective for Weight Loss [...]

DRUGS & RX: BOSTON, August 25, 2008 /PRNewswire-FirstCall/ — New data from PAREXEL International Corporation , a leading global biopharmaceutical services organization, reveal that U.S. marketing applications for new molecular entities (NMEs) surged 33 percent…

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PAREXEL Data Indicate U.S. Marketing Applications for New Molecular Entities Bounce Back was another wonderful and [...]

CANCER NEWS: Background
Candidaspongiolide (CAN), a novel polyketide from a marine sponge, is the active component of a mixture that was found to be potently cytotoxic in the National Cancer Institute’s 60-cell-line screen.

Methods
Effects of CAN on U251 glioma and HCT116 colorectal cancer cells and on normal fibroblasts were assessed using radiolabeling studies to measure protein [...]

CANCER NEWS: Background
The risk of hepatocellular carcinoma (HCC) increases with increasing level of hepatitis B virus (HBV) in serum (viral load). However, it is unclear whether genetic characteristics of HBV, including HBV genotype and specific genetic mutations, contribute to the risk of HCC. We examined the HCC risk associated with HBV genotypes and common [...]

MEDICAL NEWS:
Abstract

Background  Preventive service use among older adults is suboptimal. Unhealthy drinking may constitute a risk factor for failure to receive
these services.

Objectives  To determine the relationship between unhealthy drinking and receipt of recommended preventive services among elderly Medicare
beneficiaries, applying the framework of current alcohol consumption guidelines.

Design/Methods  The data source is the nationally representative 2003 [...]

MEDICAL NEWS:
Abstract

Background  Conflicts of interest (COI) in research are an important emerging topic of investigation and are frequently cited as a serious
threat to the integrity of human participant research.

Objective  To study financial conflicts of interest (FCOI) policies for individual investigators working in Canadian academic health
centers.

Design  Survey instrument containing 61 items related to FCOI.

Setting  All [...]

MEDICAL NEWS: New research indicates that giving patients a continuous low dose of an immune system booster, a method known as metronomic dosing, as part of a therapeutic prostate cancer vaccine strategy is safe and produces similar immune responses and fewer side effects than the more common dosing method, which is not well tolerated [...]

MEDICAL NEWS: Whether a painless, portable device that uses electrical current rather than X-ray to look for breast (boob) cancer could be an alternative to traditional mammograms is under study at the Medical College of Georgia. MCG is one of 20 centers internationally and the only place in Georgia studying new technology developed by [...]

DRUGS & RX: BETHESDA, Md., Aug. 19, 2008–The majority of deaths during the influenza pandemic of 1918-1919 were not caused by the influenza virus acting alone, report researchers from the National Institute of Allergy and Infectious Diseases (NIAID),…

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Bacterial Pneumonia Caused Most Deaths in 1918 Influenza Pandemic Implications for Future Pandemic [...]