MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]
Aug
29
Multiple imputation to correct for partial verification bias revisited
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Aug
28
Multiple imputation to correct for partial verification bias revisited
≡ Category: Cancer, Cancer Lawsuits, Doctors, Drugs & RX, Hospitals, Medical News, Mesothelioma Info, Uncategorized, Vioxx Lawsuit | ≅ Leave a Comment
MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]
Aug
27
Vioxx Payouts to Begin This Month
≡ Category: Vioxx Lawsuit | ≅ Leave a Comment
VIOXX CLASS ACTION LAWSUIT UPDATE:
Partial settlement payments will soon be in the mail to those people who claim that taking Vioxx caused them to suffer heart attacks, the Associated Press is reporting. Vioxx is the pain reliever that was linked to heart failure and has since been removed from the market. Payments are scheduled to [...]
Aug
20
Analyses of cumulative incidence functions via non-parametric multiple imputation
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MEDICAL NEWS: We describe a non-parametric multiple imputation method that recovers the missing potential censoring information from competing risks failure times for the analysis of cumulative incidence functions. The method can be applied in the settings of stratified analyses, time-varying covariates, weighted analysis of case-cohort samples and clustered survival data analysis, where no current [...]
Aug
20
Performing meta-analysis with incomplete statistical information in clinical trials
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MEDICAL NEWS: Background:
Results from clinical trials are usually summarized in the form of sampling distributions. When
full information (mean, SEM) about these distributions is given, performing meta-analysis is straightforward.
However, when some of the sampling distributions only have mean values, a challenging issue is to decide how
to use such distributions in meta-analysis. Currently, the most common [...]
Aug
14
Non-response to a life course socioeconomic position indicator in surveillance: comparison of telephone and face-to-face modes
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MEDICAL NEWS: Background:
Measurement of socioeconomic position (SEP) over the life course in population health surveillance systems is important for examining differences in health and illness between different population groups and for monitoring the impact of policies and interventions aimed at reducing health inequities and intergenerational disadvantage over time. While face-to-face surveys are considered [...]
Aug
12
ORIGINAL INVESTIGATION: Medical Records and Quality of Care in Acute Coronary Syndromes: Results From CRUSADE
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MEDICAL NEWS:
Background Patient medical records are important means of communication among health care providers. Limited evaluation has been performed of the quality of the medical records or its association with health care processes or outcomes.
Methods We performed an empirical evaluation of the completeness of medical records from 607 randomly selected patients admitted with non–ST-segment elevation [...]
Jul
23
A comparison of hospital performance with non-ignorable missing covariates: An application to trauma care data
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MEDICAL NEWS: Trauma is a term used in medicine for describing physical injury. The prospective evaluation of the care of injured patients aims to improve the management of a trauma system and acts as an ongoing audit of trauma care. One of the principal techniques used to evaluate the effectiveness of trauma care at [...]
Jul
15
A coarsened multinomial regression model for perinatal mother to child transmission of HIV
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MEDICAL NEWS: Background:
In trials designed to estimate rates of perinatal mother to child transmission of HIV, HIV assays are scheduled at multiple points in time. Still, infection status for some infants at some time points may be unknown, particularly when interim analyses are conducted.
Methods:
Logistic regression models are commonly used to estimate covariate-adjusted transmission rates, [...]
Jul
13
Why Physicians Favor Use of Percutaneous Coronary Intervention to Medical Therapy: A Focus Group Study
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MEDICAL NEWS:
Abstract
BACKGROUND Percutaneous coronary intervention (PCI) is performed in maNY (New York) patients with stable coronary artery disease, despite evidence
of little clinical benefit over optimal medical therapy.
OBJECTIVE To examine physicians’ beliefs, practices, and decision-making regarding elective PCI.
DESIGN Six focus groups, three with primary care physicians and three with cardiologists. Participants discussed PCI using hypothetical
case [...]
Jul
13
Evaluating assumptions of weighting class methods for partial response using a selection model
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MEDICAL NEWS: In survey sampling, information about the prevalence of a health outcome Y for a defined target population is frequently obtained using a two-stage data collection process. In the first stage, households that have members of the target population are identified and socio-demographic data that are believed to be associated with Y are [...]
Jul
13
A maximum likelihood latent variable regression model for multiple informants
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MEDICAL NEWS: Studies pertaining to childhood psychopathology often incorporate information from multiple sources (or informants). For example, measurement of some factor of particular interest might be collected from parents, teachers as well as the children being studied. We propose a latent variable modeling framework to incorporate multiple informant predictor data. Several related models are [...]