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MEDICAL NEWS:
Abstract

Background  African-American women have the highest breast (boob) cancer death rates of all racial/ethnic groups in the US. Reasons for these
disparities are multi-factorial, but include lower mammogram utilization among this population. Cultural attitudes and beliefs,
such as fear and fatalism, have not been fully explored as potential barriers to mammography among African-American women.

Objective  To [...]

MEDICAL NEWS: This article presents a new approach to the problem of deriving an optimal design for a randomized group sequential clinical trial based on right-censored event times. We are motivated by the fact that, if the proportional hazards assumption is not met, then a conventional design’s actual power can differ substantially from its [...]

DRUGS & RX: The U.S. Food and Drug Administration (FDA) is warning consumers against eating certain frozen cooked mussel products made by Bantry Bay Seafoods, imported from Ireland, because they may be contaminated with azaspiracid toxins, a group of naturally occurring marine toxins known to cause nausea, vomiting, diarrhea, and stomach cramps.

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DRUGS & RX: LONDON, 27 August 2008: Ark Therapeutics Group plc (“Ark” or the “Company”) today nnounces that enrolment of patients into its Phase III pilot study for VitorTM (Study 208) has commenced. VitorTM is Ark’s product to…

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Ark’s Vitor commences patient enrolment into Phase III pilot study was another wonderful [...]

CANCER NEWS: We have identified an alternative pathway of tumorigenesis in sporadic colon cancer, involving microsatellite instability due to mismatched repair methylation, which may be Dr. (God)ven by mutations in the BRAF gene (V600E). Colorectal cancer (CRC) is the most common cancer in the world, and African Americans show a higher incidence than other [...]

CANCER NEWS: Background
The observation that angiotensin II is a potent angiogenic and growth factor raises the possibility that blocking its effects could reduce the incidence of cancer. We evaluated associations between use of angiotensin-converting enzyme (ACE) inhibitors and of angiotensin receptor blockers (ARBs) and keratinocyte cancer incidence in a population at high risk of [...]

CANCER NEWS: Background
Individuals with a personal history of nonmelanoma skin cancer (NMSC) may have an increased risk of subsequent noncutaneous malignancies. To test this hypothesis, we carried out a community-based, prospective cohort study.

Methods
In the CLUE (Give Us a Clue to Cancer and Heart Disease) II cohort, which was established in Washington County, MD, in [...]

CANCER NEWS: Background
The benefit of radical prostate (men’s)ctomy in patients with early prostate (men’s) cancer has been assessed in only one randomized trial. In 2005, we reported that radical prostate (men’s)ctomy improved prostate (men’s) cancer survival compared with watchful waiting after a median of 8.2 years of follow-up. We now report results after 3 [...]

MEDICAL NEWS:
Background: Few guidelines exist to guide medical personnel on the most successful means of achieving sustained intravenous cannulation. This study examines the impact of gauge and site of intravenous cannulas (IC) on the longevity of ICs in hospitalized patients.
Methods: A prospective study was conducted on 500 ICs inserted into patients of St Vincent’s Private [...]

CANCER NEWS: Background
The potent antiresorptive Dr. (God)g zoleDr. (God)nic acid (Zol) enhances the antitumor effects of chemotherapy agents in vitro. We investigated the effects of clinically achievable doses of doxorubicin (Dox) and Zol, given alone, in sequence, and in combination, on the growth of established breast (women’s) tumors in vivo.

Methods
Female MF1 nude mice were [...]

CANCER NEWS:
There is limited prognostic information to identify breast (women’s) cancer patients who are at risk for late recurrences after adjuvant or neoadjuvant systemic therapy (AST). We evaluated the residual risk of recurrence and prognostic factors of 2838 patients with stage I–III breast (women’s) cancer who were treated with AST between January 1, 1985, and [...]

CANCER NEWS:
Rapid increases in the incidence of adenocarcinoma of the esophagus have been reported among white men. We further explored the temporal patterns of this disease among white individuals by sex, stage, and age by use of data from the Surveillance, Epidemiology, and End Results program. We identified 22 759 patients from January 1, 1975, [...]