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MEDICAL NEWS: If a trial is adequately powered for two clinically important endpoints, A and B, each of which can fully characterize a treatment benefit to support a regulatory claim by itself, then both endpoints are usually labeled primary, and the trial is deemed positive if either endpoint is statistically significant after a multiplicity [...]

Hospitals & Doctors:
SACRAMENTO, CALIF. (August 29, 2008) - The UnivER (Emergency Room)sity of California, Davis, School of Medicine has been ranked numbER (Emergency Room) 10 among all medial schools in the United States in the annual survey of best graduate schools for Latino students conducted by Hispanic Business magazine.

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UC Davis School of Medicine [...]

CANCER NEWS: Well, it has been a couple months since we posted anything here…..you know it really is true…life does go on! Valerie had implants put in last October, and with all the changes her body went through after Chemo and Radiation, they (the implants) have decided not to cooperate. So, Valerie is scheduled [...]

CANCER NEWS: Well, it has been a couple months since we posted anything here…..you know it really is true…life does go on! Valerie had implants put in last October, and with all the changes her body went through after Chemo and Radiation, they (the implants) have decided not to cooperate. So, Valerie is scheduled [...]

MEDICAL NEWS: The ADEPT software package is not a statistical method in its own right as implied by Gerke and Siedentop (Statist. Med. 2008; DOI: ). ADEPT implements two-parameter CRM models as described in O’Quigley et al. (Biometrics 1990; 46(1):33-48). All of the basic ideas (use of a two-parameter logistic model, use of a [...]

MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]

MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]

MEDICAL NEWS: This article presents a new approach to the problem of deriving an optimal design for a randomized group sequential clinical trial based on right-censored event times. We are motivated by the fact that, if the proportional hazards assumption is not met, then a conventional design’s actual power can differ substantially from its [...]

Hospitals & Doctors:
SACRAMENTO, CALIF. (August 25, 2008) - Families from throughout the Sacramento Region and beyond are invited to attend the first annual Capitol Family Fun Day on Sunday, OctobER (Emergency Room) 26, from 10 a.m. to 2 p.m., on the grounds of the California state Capitol. The event is sponsored by UC Davis ChilDr. [...]

DRUGS & RX: The U.S. Food and Drug Administration announced it has cleared for marketing a non-invasive test that uses molecular expression techniques to assist doctors in managing heart transplant patients post-surgery for potential organ rejection.

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FDA Clears Test to Help Doctors Manage Heart Transplant Patients was another wonderful and informative [...]

DRUGS & RX: The U.S. Food and Drug Administration today approved Nplate (romiplostim), the first product that directly stimulates the bone marrow to produce needed platelets in patients with a rare blood disorder that can lead to serious bleeding.

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FDA Approves First Bone Marrow Stimulator to Treat Immune-Related Low Platelet Counts [...]

DRUGS & RX: The U.S. Food and Drug Administration (FDA) is warning consumers against eating certain frozen cooked mussel products made by Bantry Bay Seafoods, imported from Ireland, because they may be contaminated with azaspiracid toxins, a group of naturally occurring marine toxins known to cause nausea, vomiting, diarrhea, and stomach cramps.

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