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MEDICAL NEWS:
Abstract

Background  Physicians, influenced by various pressures, may document information in patient records that they did not personally observe.

Objective  To evaluate the hospital chart documentation practices of internists and internal medicine sub-specialists in the Northeastern
United States.

Design  An anoNY (New York)mous mail survey questionnaire.

Participants  One thousand one hundred twenty-six randomly selected internists and internal medicine sub-specialists.
[...]

MEDICAL NEWS:
Abstract

Background  African-American women have the highest breast (boob) cancer death rates of all racial/ethnic groups in the US. Reasons for these
disparities are multi-factorial, but include lower mammogram utilization among this population. Cultural attitudes and beliefs,
such as fear and fatalism, have not been fully explored as potential barriers to mammography among African-American women.

Objective  To [...]

MEDICAL NEWS:
Brief Report: Coronary Heart Disease Events Associated with Hormone Therapy in Younger and Older Women

Content Type Journal Article
Category Erratum
DOI 10.1007/s11606-008-0762-2
Authors

Shelley R. Salpeter, Santa Clara Valley Medical Center Department of Medicine San Jose CA USA
Judith M. E. Walsh, University of California, San Francisco Department of Medicine San Francisco CA USA
Elizabeth Greyber, Santa Clara Valley Medical [...]

MEDICAL NEWS: If a trial is adequately powered for two clinically important endpoints, A and B, each of which can fully characterize a treatment benefit to support a regulatory claim by itself, then both endpoints are usually labeled primary, and the trial is deemed positive if either endpoint is statistically significant after a multiplicity [...]

MEDICAL NEWS: The ADEPT software package is not a statistical method in its own right as implied by Gerke and Siedentop (Statist. Med. 2008; DOI: ). ADEPT implements two-parameter CRM models as described in O’Quigley et al. (Biometrics 1990; 46(1):33-48). All of the basic ideas (use of a two-parameter logistic model, use of a [...]

MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]

MEDICAL NEWS: Partial verification refers to the situation where a subset of patients is not verified by the reference (gold) standard and is excluded from the analysis. If partial verification is present, the observed (naive) measures of accuracy such as sensitivity and specificity are most likely to be biased. Recently, Harel and Zhou showed [...]

MEDICAL NEWS: This article presents a new approach to the problem of deriving an optimal design for a randomized group sequential clinical trial based on right-censored event times. We are motivated by the fact that, if the proportional hazards assumption is not met, then a conventional design’s actual power can differ substantially from its [...]

MEDICAL NEWS: Background:
Animal data show that decreased activity of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2), which potently inactivates glucocorticoids (e.g. cortisol) to inert forms (cortisone), allows increased access of maternal glucocorticoids to the fetus and ‘programs’ hypertension. Data in humans are limited. We examined in humans the association between venous umbilical cord blood [...]

MEDICAL NEWS: No Abstract.

Type 1 Diabetes Mellitus: New Knowledge of Etiology, New Approaches to Management - Another great medical article from iHateHospitals.com!

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Variation in breast cancer risk [...]

MEDICAL NEWS: Type 1 diabetes is one of the most well-characterized autoimmune diseases. Type 1 diabetes compromises an individual’s insulin production through the autoimmune destruction of pancreatic [beta]-cells. Although much is understood about the mechanisms of this disease, multiple potential contributing factors are thought to play distinct parts in triggering type 1 diabetes. The [...]

MEDICAL NEWS: Interventions targeting the treatment of diabetic complications have not been nearly as successful as initially estimated, despite a marked improvement in therapeutic options for diabetes. The need for understanding why some very promising interventions have failed demands a closer look at the pathomechanisms of the complications. Great strides have been made in [...]